Computational Systems Biology Group

Department of Bioengineering, Gebze Technical University, TURKEY

Pınar Pir, Group Leader

Assistant Professor

Gebze Technical University Pinar Pir
Detailed CV
Department of Bioengineering
Computational Systems Biology Group
Gebze-Kocaeli
TURKEY
Mail: pinarpir [at] gtu.edu.tr
Room: Bioengineering Building, 145
Phone: +90 262 605 33 23

Introduction

I have received my B.Sc, M.Sc and Ph.D degrees from Department of Chemical Engineering at Bogazici University, Istanbul. My PhD thesis research mainly involved integrative analysis of omics data (metabolomics and transcriptomics) from yeast growing in carbon or nitrogen limited chemostats, and it was partly a collaborative project with Prof. Stephen G Oliver.

I worked as a postdoctoral research associate in the UK between 2006-2015. I worked on yeast systems biology (Oliver Lab), metabolic modelling of biofuel production by microbes (Novacta Biosystems ) and kinetic modelling of signalling pathways in stem cells (Le Novere Lab).

As of November 2015, I am leading the Pirism Lab in CSB group at the Department of Bioengineering in Gebze Technical University, TURKEY.

Research Areas

Research in Pirism Lab is mostly based on use of NGS data in systems modelling. We are particularly interested in analysis and modelling of dynamic processes such as stem cell differentiation and tumour growth. We use single cell NGS data to be able to represent the heterogeneity in the cell populations accurately in our models, which involves use of machine learning methods as well as rigorous statistical analysis of the data. We aim to extend our models to 3-dimensions to accurately describe the cells in the context of their extracellular environment, which in turn regulates the intracellular dynamics via signalling pathways. Better understanding the dynamics of cellular processes and interactions may lead to discovery of targets to regulate these processes by human intervention.

Research Projects

Teaching

Selected Publications

For a full list of publications, see my Google Scholar page.