TOP-DOWN APPROACH
The focus is prediction of metabolic networks by the analysis of metabolome data using statistical and optimization-based techniques. Omics data is processed in such a way that the underlying network can be inferred.
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Selected Publications
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Sparsity as cellular objective to infer directed metabolic networks from steady-state metabolome data: A theoretical analysis
- PLoS ONE, 8:12, e84505 (2013)
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Metabolic network discovery through reverse engineering of metabolome data
- Metabolomics, 318-329, (2009), Citation: 19