//LAC_up : 1 NADcyt + 1 LAC = 1 NADHcyt + 1 PYR .
//ETH_up : 1 ETHX = 1 ETOH .
//AC_up : 1 ACEX = 1 AC .
//GOH_up : 1 ATP + 1 GOH = 1 ADP + 1 GOH3P .
//ADH2 : 1 ETOH + 1 NADcyt = 1 NADHcyt + 1 ACAL .
-ENZREV 
NH3_up  ADH1 ACO LSC FUM1 MDH1 ENO GPM PGK1 TPI FBA1 PGI1 RKI1 RPE TKL TAL1 TKL2 TDH GPD MDH2 AAT12 ASN12 ALT12 BAT12L BAT2V SHM12 AGX1 ADH3 

-ENZIRREV 
ALD6 ACS CAT2 CIT13 IDP1 KGD SDH MAE PDA PYC PCK1 PYK FBP1 ZWF1 SOL GND BIOMX-cmol NADHX FADHX MAINT PFK GLK GOHX PDC OSM1 ALD4 IDP2 ACETR CO2TR IDH ICL1 MLS1 CIT2 SUCTR ALD2_3 O2_UPT ADH2 GDH13 GDH2 GLN1 GLT1 GAD1 UGA1 UGA2 ASP3 ILV26 ILV5 ILV3 LEU4 LEU2 SER333 SER1 SER2 CHA1p GCV1 AICARsyn BIOMX05-AA C1tr AC_up GOH_up ETHTR ETH_up BIOMX05-AA-F03 GLC_up

-METINT 
ETOH  GLUC  NADcyt  NADHcyt  NADHmit  NADmit  AC  ACAL  ACCOAmit  ACCOAcyt  NADPHcyt  NADPcyt  NADPHmit  NADPmit  ATP  ADP  CIT  ICIT  AKG  OAC  PEP  PYR  SUC  SUCCOA  CO2  FUM  MAL  GLYO  P2G  P3G  P13G  GA3P  DHAP  FDP  F6P  G6P  G15L  P6G  RBL5P  X5P  RB5P  E4P  S7P  FADH2  FAD  O2  GOH3P  AICAR  NH3  GLT  GLN  SUCSAL  GABA  ASP  ASN  ALA  ACLAC  DHVAL  IPPMAL  OICAP  VAL  LEU  OIVAL  PHP  P3SER  SER  GLY  C1  

-METEXT 
BIOM  GLUCEX  GOH  ACEX  CO2EX  SUCEX  O2ext  NH3xt  ETHX

-CAT
ADH1 : 1 NADHcyt + 1 ACAL = 1 ETOH + 1 NADcyt .
ALD6 : 1 ACAL + 1 NADPcyt = 1 AC + 1 NADPHcyt .
ACS : 1 AC + 2 ATP = 1 ACCOAcyt + 2 ADP .
CAT2 : 1 ACCOAcyt = 1 ACCOAmit .
CIT13 : 1 ACCOAmit + 1 OAC = 1 CIT .
ACO : 1 CIT = 1 ICIT .
IDP1 : 1 NADPmit + 1 ICIT = 1 NADPHmit + 1 AKG + 1 CO2 .
KGD : 1 NADmit + 1 AKG = 1 NADHmit + 1 SUCCOA + 1 CO2 .
LSC : 1 ADP + 1 SUCCOA = 1 ATP + 1 SUC .
SDH : 1 SUC + 1 FAD = 1 FUM + 1 FADH2 .
FUM1 : 1 FUM = 1 MAL .
MDH1 : 1 NADmit + 1 MAL = 1 NADHmit + 1 OAC .
MAE : 1 NADPmit + 1 MAL = 1 NADPHmit + 1 PYR + 1 CO2 .
PDA : 1 NADmit + 1 PYR = 1 NADHmit + 1 ACCOAmit + 1 CO2 .
PYC : 1 ATP + 1 PYR + 1 CO2 = 1 ADP + 1 OAC .
PCK1 : 1 ATP + 1 OAC = 1 ADP + 1 PEP + 1 CO2 .
PYK : 1 ADP + 1 PEP = 1 ATP + 1 PYR .
ENO : 1 PEP = 1 P2G .
GPM : 1 P2G = 1 P3G .
PGK1 : 1 ATP + 1 P3G = 1 ADP + 1 P13G .
TPI : 1 DHAP = 1 GA3P .
FBP1 : 1 FDP = 1 F6P .
FBA1 : 1 FDP = 1 GA3P + 1 DHAP .
PGI1 : 1 F6P = 1 G6P .
ZWF1 : 1 NADPcyt + 1 G6P = 1 NADPHcyt + 1 G15L .
SOL : 1 G15L = 1 P6G .
GND : 1 NADPcyt + 1 P6G = 1 NADPHcyt + 1 CO2 + 1 RBL5P .
RKI1 : 1 RB5P = 1 RBL5P .
RPE : 1 RBL5P = 1 X5P .
TKL : 1 X5P + 1 RB5P = 1 GA3P + 1 S7P .
TAL1 : 1 GA3P + 1 S7P = 1 F6P + 1 E4P .
TKL2 : 1 X5P + 1 E4P = 1 GA3P + 1 F6P .
NADHX : 20 NADHmit + 24 ADP + 10 O2 = 20 NADmit + 24 ATP .
FADHX : 24 ADP + 20 FADH2 + 10 O2 = 24 ATP + 20 FAD .
MAINT : 1 ATP = 1 ADP .
TDH : 1 NADcyt + 1 GA3P = 1 NADHcyt + 1 P13G .
PFK : 1 ATP + 1 F6P = 1 ADP + 1 FDP .
GLK : 1 ATP + 1 GLUC = 1 ADP + 1 G6P .
GPD : 1 NADHcyt + 1 DHAP = 1 NADcyt + 1 GOH3P .
GOHX : 1 GOH3P = 1 GOH .
PDC : 1 PYR = 1 ACAL + 1 CO2 .
OSM1 : 1 FUM + 1 FADH2 = 1 SUC + 1 FAD .
ALD4 : 1 NADmit + 1 ACAL = 1 NADHmit + 1 AC .
IDP2 : 1 NADPcyt + 1 ICIT = 1 NADPHcyt + 1 AKG + 1 CO2 .
CO2TR : 1 CO2 = 1 CO2EX .
IDH : 1 NADmit + 1 ICIT = 1 NADHmit + 1 AKG + 1 CO2 .
ICL1 : 1 ICIT = 1 SUC + 1 GLYO .
MLS1 : 1 ACCOAcyt + 1 GLYO = 1 MAL .
CIT2 : 1 ACCOAcyt + 1 OAC = 1 CIT .
MDH2 : 1 NADcyt + 1 MAL = 1 NADHcyt + 1 OAC .
SUCTR : 1 SUC = 1 SUCEX .
O2_UPT : 1 O2ext = 1 O2 .
NH3_up : 1 NH3xt = 1 NH3 .
GDH13 : 1 NADPHcyt + 1 AKG + 1 NH3 = 1 NADPcyt + 1 GLT .
GDH2 : 1 NADcyt + 1 GLT = 1 NADHcyt + 1 AKG + 1 NH3 .
GLN1 : 1 ATP + 1 NH3 + 1 GLT = 1 ADP + 1 GLN .
GLT1 : 1 NADHcyt + 1 AKG + 1 GLN = 1 NADcyt + 2 GLT .
GAD1 : 1 GLT = 1 CO2 + 1 GABA .
UGA1 : 1 AKG + 1 GABA = 1 GLT + 1 SUCSAL .
UGA2 : 1 NADPcyt + 1 SUCSAL = 1 NADPHcyt + 1 SUC .
AAT12 : 1 OAC + 1 GLT = 1 AKG + 1 ASP .
ASN12 : 2 ATP + 1 GLN + 1 ASP = 2 ADP + 1 GLT + 1 ASN .
ASP3 : 1 ASN = 1 NH3 + 1 ASP .
ALT12 : 1 PYR + 1 GLT = 1 AKG + 1 ALA .
ILV26 : 2 PYR = 1 CO2 + 1 ACLAC .
ILV5 : 1 NADPHmit + 1 ACLAC = 1 NADPmit + 1 DHVAL .
ILV3 : 1 DHVAL = 1 OIVAL .
LEU4 : 1 ACCOAmit + 1 OIVAL = 1 IPPMAL .
LEU2 : 1 NADcyt + 1 IPPMAL = 1 NADHcyt + 1 CO2 + 1 OICAP .
BAT12L : 1 GLT + 1 OICAP = 1 AKG + 1 LEU .
BAT2V : 1 GLT + 1 OIVAL = 1 AKG + 1 VAL .
SER333 : 1 NADcyt + 1 P3G = 1 NADHcyt + 1 PHP .
SER1 : 1 GLT + 1 PHP = 1 AKG + 1 P3SER .
SER2 : 1 P3SER = 1 SER .
SHM12 : 1 SER = 1 GLY + 1 C1 .
AGX1 : 1 GLYO + 1 ALA = 1 PYR + 1 GLY .
GCV1 : 1 NADmit + 1 GLY = 1 NADHmit + 1 CO2 + 1 NH3 + 1 C1 .
AICARsyn : 6 ATP + 1 CO2 + 1 RB5P + 2 GLN + 1 ASP + 1 GLY + 1 C1 = 6 ADP + 1 FUM + 1 AICAR + 2 GLT .
ADH3 : 1 NADHmit + 1 ACAL = 1 ETOH + 1 NADmit .
ETHTR : 1 ETOH = 1 ETHX .
BIOMX05-AA-F03 : 0.01749 NADcyt + 0.01456 NADmit + 0.0203 ACCOAcyt + 0.08352 NADPHcyt + 0.01051 NADPHmit + 1.6847 ATP + 0.01568 PEP + 0.0049 PYR + 0.06633 G6P + 0.00575 RB5P + 0.00784 E4P + 0.00065 GOH3P + 0.00062 AICAR + 0.04204 GLT + 0.0162 GLN + 0.03077 ASP + 0.00303 ASN + 0.01363 ALA + 0.00787 VAL + 0.00879 LEU + 0.00701 SER + 0.00861 GLY + 0.00457 C1 = 0.01749 NADHcyt + 0.01456 NADHmit + 0.08352 NADPcyt + 0.01051 NADPmit + 1.6847 ADP + 0.02798 AKG + 0.00607 OAC + 0.02578 CO2 + 0.00083 P3G + 1 BIOM + 0.00573 NH3 .
ACETR : 1 AC = 1 ACEX .
GLC_up : 1 GLUCEX = 1 GLUC .